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Abstract #4925

Comprehensive MRI reveals compromised baseline cardiac function in lung cancer patients undergoing radiation therapy treatment

El-Sayed H Ibrahim1, Elizabeth Gore1, Sherry-Ann Brown1, and Carmen Bergom2
1Medical College of Wisconsin, Milwaukee, WI, United States, 2Washington University, St Louis, MO, United States

Synopsis

Along with systemic therapies, radiation therapy (RT) plays a key role in treating lung cancer, despite high incidence of RT-induced cardiac complications. Most lung cancer patients present with cardiac risk factors that result in compromised baseline cardiac function that puts the patients at higher risk of developing cardiac complications. In this study, we investigate characteristics of baseline cardiovascular function in lung cancer patients undergoing RT. The results showed that the patients had borderline cardiac function and reduced myocardial strain measurements. Myocardial T1/T2 values in the patients were slightly high and the hemodynamic measurements showed different pattern than that in volunteers.

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