Multiparametric magnetic resonance imaging (mpMRI) has a significant impact on prostate cancer (PCa) diagnosis. However, it is important to realize its accuracy for PCa detection. In this study, we compare mpMRI with whole-mount histopathology (WMHP) images as a reference to discover the limitation of mpMRI for PCa lesion localization. The results are presented as a spatial probability map, corresponding to the prostate sector map used in Prostate Imaging Reporting and Data System version 2.1 (PI-RADSv2.1), to highlight the regions on the prostate glands that require further attention from clinicians for a more accurate diagnosis of PCa and its treatment planning.
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