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Abstract #5013

High resolution 3D whole brain T1, T2, T2* and QSM mapping within 3.5 mins

Jinwei Zhang1, Thanh Nguyen2, Eddy Solomon2, Hang Zhang1, Chao Li1, Alexey Dimov2, Pascal Spincemaille2, and Yi Wang2
1Cornell University, New York, NY, United States, 2Weill Cornell Medicine, New York, NY, United States

Synopsis

A 3D whole brain T1, T2, T2*, QSM mapping pipeline was proposed for fast multi-parametric quantitative imaging. A multi-echo gradient echo (mGRE) sequence with varying sampling patterns along echoes was implemented to acquire signals for T2* and QSM mapping. A multi-contrast MR fingerprinting (MRF) sequence with both inversion recovery and T2 preparation pulses and varying sampling patterns among contrasts was implemented to acquire signals for T1 and T2 mapping. A deep ADMM network was used to reconstruct mGRE images. The magnitude image from reconstructed mGRE images was used to guide the reconstruction of MRF images with directional joint TV regularization.

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Keywords