Abstract #5041

Impact of gradient scheme and shimming on out-of-voxel echo artefacts in edited MRS

Yulu Song^1,2, Helge J. Zöllner^1,2, Steve C.N. Hui^1,2, Georg Oeltzschner^1,2, and Richard A.E. Edden^1,2

¹Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, United States, ²F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States

Synopsis

Out-of-voxel (OOV) signal is a common spurious echo artifact, which interferes with spectral quantification. These signals arise from either incomplete suppression or accidental refocusing. Dephasing Optimization Through Coherence Order Pathway Selection (DOTCOPS) is an optimized gradient scheme that can be used to suppress unwanted signals. Here we explored the impact of gradient scheme and shimming-order on OOV artefacts in Hadamard-encoded edited MRS.

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