Abstract #5045

PET Recon with MR Priors: Application in Ambiguously Rated Amyloid PET Scans

Mehdi Khalighi¹, Greg Zaharchuk¹, Michael Zeineh¹, Guido Davidzon¹, Gabriel Kennedy², Christina Young¹, Michael Greicius², Kathleen Poston², and Elizabeth Mormino²

¹Radiology, Stanford University, Stanford, CA, United States, ²Neurology, Stanford University, Stanford, CA, United States

Synopsis

A recently developed PET recon with MR priors and motion correction method is applied to a set of ambiguously rated amyloid PET scans and is compared with regular TOF-OSEM PET recon using SUVR. The same comparison is done in a set of scans which were matched by clinical diagnosis. By using PET recon with MR priors, lower SUVRs for negative scans compared to increased SUVRs for positive scans were measured, which shows improvement in the ability to distinguish intermediate amyloid levels.

This abstract and the presentation materials are available to members only; a login is required.

Join Here