Keywords: Liver, Spectroscopy31P MRS can be used in liver disease diagnosis and treatment monitoring. However, it is unclear whether 31P metabolite concentrations differ across the healthy liver, which would be important to take into account. Using an integrated 31P whole-body transmit coil for a 7T MRI scanner in combination with a 16-channel body receive array, we aimed to assess spatial variations of 31P metabolites within the liver in healthy subjects. We showed that there is significant spatial heterogeneity of various 31P metabolites levels within the liver, with marked differences for the PME and PDE metabolites between the left and right lobe.
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