Keywords: Neuroinflammation, Infectious disease, Alcohol UseChronic alcohol use and HIV infection can have synergistic effects that negatively impact the brain leading to abnormalities such as neuro-inflammation. Free-water eliminated DTI (FWE-DTI) has been suggested as a biomarker of neuro-inflammation. This study compare DTI and FWE-DTI derived metrics in the brains of HIV+/HIV- chronic drinkers to determine whether HIV infection or drinking behavior is a more significant factor contributing to brain microstructural abnormalities and neuro-inflammation. Our results suggest that HIV is a more significant factor than drinking level contributing to elevated free water in the brain as a sign of neuro-inflammation.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords