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Abstract #0045

Motion robust MR Fingerprinting scans for non-sedated infant imaging

Chaitra Badve1, Jessie EP Sun2, Ameya Nayate1, Michael Wien1, Douglas Martin1, Jared Durieux1, Chris Flask2, Deanne Wilson Costello3, and Dan Ma4
1Radiology, University Hospitals Cleveland Medical Center, Cleveland, OH, United States, 2Radiology, Case Western Reserve University, Cleveland, OH, United States, 3Neonatology, University Hospitals Cleveland Medical Center, Cleveland, OH, United States, 4Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States

Synopsis

Keywords: Neonatal, MR FingerprintingThe 5 min high resolution MRF scans coupled with low-rank iterative reconstruction successfully generated perfectly co-registered T1, T2 maps, synthetic MR contrast images, R1R2 maps, and myelin water fraction maps. Image Quality Assessment analysis with three pediatric neuroradiologists found that MRF based synthetic T1w and T2w images quality were superior in quality to MRI T1w and T2w (p<.0001) with lower image artifacts in the MRF synthetic images as compared to standard of care MRI. MRF T1w images demonstrated better myelin visualization compared to clinical T1w, and MRF T2w demonstrated improved tissue structure visualization as compared to clinical T2w images.

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Keywords