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Abstract #0056

Respiratory-motion-corrected simultaneous 3D T1, T2, and fat-fraction mapping at 0.55T, for comprehensive characterization of liver tissue

Donovan Tripp1, Karl P Kunze1,2, Michael Crabb1, Radhouene Neji1,2, Claudia Prieto1,3, and René Botnar1,3,4
1School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2MR Research Collaborations, Siemens Healthcare Limited, Camberley, United Kingdom, 3School of Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, 4Institute for Biological and Medical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile

Synopsis

Keywords: Liver, Low-Field MRIThrough T1, T2, and fat fraction mapping, MRI is a formidable tool for the comprehensive assessment of liver health, but has been held back by slow, 2D, single-parameter mapping sequences. We propose a novel respiratory-motion-corrected framework to acquire all three of these maps from a single 6.5-minute scan, on the latest generation of 0.55T scanner. The resulting maps are 3D, with 3 mm isotropic resolution, and co-registered, making them suitable for multiparametric assessment of tissue health. Liver joint T1, T2, and fat fraction maps are in good agreement with reference values and first in-vivo scans provide promising image quality.

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Keywords