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Abstract #0076

Confidence Maps for Reliable Proton Density Fat-Fraction and R2* Estimation

Daiki Tamada1, Rianne A Van der Heijden1, Diego Hernando1,2,3,4, and Scott B Reeder1,2,4,5,6
1Radiology, University of Wisconsin-Madison, Madison, WI, United States, 2Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, 3Electrical and Computer Engineering, University of Wisconsin-Madison, Madison, WI, United States, 4Biomedical Engineering, University of Wisconsin-Madison, Madison, WI, United States, 5Medicine, University of Wisconsin-Madison, Madison, WI, United States, 6Emergency, University of Wisconsin-Madison, Madison, WI, United States

Synopsis

Keywords: Data Processing, Artifacts, CSE-MRIIn this work we develop a confidence map algorithm to identify reliable estimates of PDFF and R2* for CSE-MRI in the liver. Reliability of estimates is evaluated based on a normalized root-mean-square-error (NRMSE) between measured and model signals. Threshold values of the NRMSE are determined by using the Cramér–Rao Lower Bound. Monte-Carlo simulations and clinical CSE-MRI successfully validate the proposed method.

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Keywords