Abstract #0078

Optimized 7 T Cortical Magnetization Transfer Saturation Imaging: Application to Cortical Myelin Imaging in Multiple Sclerosis

Risavarshni Thevakumaran^1,2, Marcus Couch^2,3,4, Sridar Narayanan^2,3, Douglas Arnold ^2,3, and David Rudko^1,2,3

¹Department of Biological and Biomedical Engineering, McGill University, Montreal, QC, Canada, ²McConnell Brain Imaging Centre, Montreal Neurological Institute and Hospital, Montreal, QC, Canada, ³Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada, ⁴Siemens Healthcare Limited, Montreal, QC, Canada

Synopsis

Keywords: Data Processing, High-Field MRI, Quantitative MRIWe designed an MRI protocol for rapid, high-resolution human cortical MTsat (csMTsat) imaging at 7 T. Our approach leveraged the PTx capability of the 7 T Siemens Terra MRI system. Further, we developed a post-processing scheme that reduces residual B1+ field bias and noise in csMTsat maps for imaging cortical myelin in the human cortex at high-resolution, which can be applied to study cortical demyelination in Multiple Sclerosis.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.