Abstract #0108

Efficient iT2prep-BOOST for simultaneous contrast-free 3D aortic lumen and vessel wall imaging for the assessment of thoracic aortopathy

Anastasia Fotaki¹, Camila Munoz¹, Alina Hua¹, Karl P Kunze^1,2, Radhouene Neji³, Kuberan Pushparajah¹, Rene M Botnar^4,5,6,7, and Claudia Prieto^4,5,6,7

¹King's College London, London, United Kingdom, ²MR Research Collaborations, Siemens Healthcare Limited, Camberley, United Kingdom, ³MR Research Collaborations, Siemens Healthcare Limited, Camberely, United Kingdom, ⁴Biomedical Engineering, King's College London, London, United Kingdom, ⁵Institute for Biological and Medical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, ⁶Millennium Institute for Intelligent Healthcare Engineering, Santiago, Chile, ⁷School of Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile

Synopsis

Keywords: Data Acquisition, Cardiovascular, aortaBright- and black-blood MRI sequences are clinically acquired sequentially, for aortic lumen and vessel wall imaging respectively, in patients with thoracic aortic disease. A novel, free-breathing, 3D sequence (iT2prep-BOOST) is proposed for contrast-free simultaneous depiction of lumen and vessel wall. We clinically validated the iT2prep-BOOST in a cohort of 25 patients with thoracic aortic disease against the conventional bright-blood T2-prep bSSFP sequence and black-blood 2D HASTE. Quantitative and qualitative image quality assessment demonstrated that iT2Prep-BOOST enabled time-efficient, bright- and black-blood aortic imaging, with improved image quality compared to conventional approaches, and comparable measurements for aortic wall and lumen dimensions.

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