Abstract #0124

Effects of Levodopa Therapy on Neurovascular Coupling in Parkinson’s Disease Patients

Chenqing Wu¹, Haoting Wu¹, Cheng Zhou¹, Jingwen Chen¹, Jiaqi Wen¹, Xiaocao Liu¹, Jianmei Qin¹, Zhengye Cao¹, Tao Guo¹, Xiaojun Guan¹, Xiaojun Xu¹, Baorong Zhang², and Minming Zhang¹

¹Department of Radiology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China, ²Department of Neurology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China

Synopsis

Keywords: Parkinson's Disease, Neurodegeneration

Abnormal neurovascular coupling was found in PD patients. These impairments were partially normalized after levodopa therapy, and ALFF alterations played a primary role in this normalization effect.

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