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Abstract #0173

Myocardial T Mapping in Small Animals: Comparison of Balanced Spin-Lock and Malcolm-Levitt Preparations

Maximilian Gram1,2, Petra Albertova1,2, Fabian Tobias Gutjahr2, Peter Michael Jakob2, Wolfgang Rudolf Bauer3,4, Peter Nordbeck1,4, and Martin Christa1,4
1Department of Internal Medicine I, University Hospital Würzburg, Würzburg, Germany, 2Experimental Physics 5, University of Würzburg, Würzburg, Germany, 3Department of Internal Medicine I, Divisions of Cardiology and Nephrology, University Hospital Würzburg, Würzburg, Germany, 4Comprehensive Heart Failure Center (CHFC), Würzburg, Germany

Synopsis

Keywords: Relaxometry, Quantitative Imaging, Spin-Lock, T1ρ, T2ρIn this work, we propose myocardial T mapping as a potential and more robust alternative to conventional T2 quantification. Our new approach for T imaging, which is based on Malcolm-Levitt preparations with zero inter-pulse delays, was compared with established pulse sequences for T2, T and T in both phantom and in vivo experiments. In summary, the new preparatory pulse sequence was shown to meet the demanding requirements of myocardial T mapping at high magnetic field strength and to outperform conventional T preparations using balanced spin-locking.

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