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Abstract #0179

Free-Breathing Simultaneous Native Myocardial T1, T2, and T1ρ Mapping with Cartesian Acquisition and Dictionary Matching

Zhenfeng Lv1,2, Sha Hua3, Rui Guo4, Bowen Shi5, Peng Hu1,2, and Haikun Qi1,2
1School of Biomedical Engineering, ShanghaiTech University, Shanghai, China, 2Shanghai Clinical Research and Trial Center, Shanghai, China, 3Department of Cardiovascular Medicine, Ruijin Hospital Lu Wan Branch, Shanghai Jiao Tong University School of Medicine, Shanghai, China, 4School of Medical Technology, Beijing Institute of Technology, Beijing, China, 5iHuman Institute, School of Life Science and Technology, ShanghaiTech University, Shanghai, China

Synopsis

Keywords: Myocardium, Tissue Characterization

T1 and T2 are well-recognized parameters for detecting various cardiomyopathies, and T1ρ is an endogenous contrast for myocardial fibrosis. Multi-parametric cardiac MRI can provide co-registered parameter maps for comprehensive diagnosis and account for the interparameter dependency for more accurate quantification. Therefore, we propose a free-breathing simultaneous T1, T2, and T1ρ mapping technique with single-shot Cartesian acquisition and dictionary matching for parameter quantification. The phantoms results indicated the good accuracy and insensitiveness to heart rates of the proposed technique. Using prospective through-plane and retrospective in-plane motion correction, the proposed method generated similar in vivo mapping quality to breath-hold mapping methods.

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