Abstract #0179

Free-Breathing Simultaneous Native Myocardial T1, T2, and T1ρ Mapping with Cartesian Acquisition and Dictionary Matching

Zhenfeng Lv^1,2, Sha Hua³, Rui Guo⁴, Bowen Shi⁵, Peng Hu^1,2, and Haikun Qi^1,2

¹School of Biomedical Engineering, ShanghaiTech University, Shanghai, China, ²Shanghai Clinical Research and Trial Center, Shanghai, China, ³Department of Cardiovascular Medicine, Ruijin Hospital Lu Wan Branch, Shanghai Jiao Tong University School of Medicine, Shanghai, China, ⁴School of Medical Technology, Beijing Institute of Technology, Beijing, China, ⁵iHuman Institute, School of Life Science and Technology, ShanghaiTech University, Shanghai, China

Synopsis

Keywords: Myocardium, Tissue Characterization

T1 and T2 are well-recognized parameters for detecting various cardiomyopathies, and T1ρ is an endogenous contrast for myocardial fibrosis. Multi-parametric cardiac MRI can provide co-registered parameter maps for comprehensive diagnosis and account for the interparameter dependency for more accurate quantification. Therefore, we propose a free-breathing simultaneous T1, T2, and T1ρ mapping technique with single-shot Cartesian acquisition and dictionary matching for parameter quantification. The phantoms results indicated the good accuracy and insensitiveness to heart rates of the proposed technique. Using prospective through-plane and retrospective in-plane motion correction, the proposed method generated similar in vivo mapping quality to breath-hold mapping methods.

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