Meeting Banner
Abstract #0183

Free-breathing, Whole-heart, High-dynamic-range Quantitative Susceptibility Mapping (HDR-QSM) for Imaging Hemorrhagic Infarctions

Yuheng Huang1,2, Xingmin Guan1, Xinheng Zhang1,2, Liqi(Richard) Tang 1, Xiaoming Bi3, Fei Han3, HsuLei Lee4, Hui Han4, Anthony Christodoulou4, Debiao Li4, Rohan Dharmakumar1, and Hsin-Jung Yang4
1krannert cardiovascular research center, Indiana University school of medicine, Indianapolis, IN, United States, 2Bioengineering, UCLA, LA, CA, United States, 3Siemens Healthineers, Malvern, PA, United States, 4Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States

Synopsis

Keywords: Myocardium, Cardiovascular, hemorrhagic reperfusion injury myocardial infarctionAccurately detecting and quantifying intramyocardial hemorrhage(IMH) is critical for patient management. QSM has evolved into the standard method for iron imaging. However, obtaining cardiac QSM for IMH evaluation is difficult due to well-known technical challenges. Here, we developed a motion-robust 3D multi-echo GRE technique and combined them with a high-dynamic-range QSM algorithm to derive reliable QSM maps in IMH hearts. We tested and validated it in phantom, ex-vivo, and in-vivo IMH hearts in animal models. We demonstrated that the proposed method could accurately detect IMH and reliably quantify iron concentration with a free-breathing scan under 6 minutes.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords