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Abstract #0189

High spatial resolution quantitative susceptibility mapping using in-phase echoes enables the depiction of breast microcalcifications

Christof Boehm1, Alexander Komenda1, Kilian Weiss2, Jonathan K. Stelter1, Tabea Borde1, Jakob Meineke3, Marcus R. Makowski1, Eva M. Fallenberg1, and Dimitrios C. Karampinos1
1Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany, 2Philips GmbH Market DACH, Hamburg, Germany, 3Philips Research, Hamburg, Germany

Synopsis

Keywords: Breast, SusceptibilityBreast microcalcifications (MCs) can be the only sign of carcinoma and other precursor lesions of breast cancer in x-ray mammography. Mammography is routinely used for population-based breast cancer screening. However, due to the ionizing nature of x-ray radiation, the use of an MR-based technique would be desirable for repeated examinations especially in screening targeted sub-cohorts at high-risk or younger women. In this work, we present initial results on the visualization of MCs using MR with an optimized high-resolution GRE-scan and quantitative susceptibility mapping. The proposed methodology allows for the robust visualization of MC clusters in MR for the first time.

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