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Abstract #0192

High-resolution DWI in the breast by Spatiotemporal encoding (SPEN): clinical utility in comparison with SS-EPI and RESOLVE

Rena Nakayama1, Mami Iima2,3, Masako Kataoka2, Maya Honda2,4, Yuta Urushibata5, Martins Otikovs6, Noam Nissan7, Lucio Frydman6, Rie Ota2,8, Aika Okazawa2, Kazuki Tsuji1, Masakazu Toi9, and Yuji Nakamoto2
1Kyoto University Faculty of Medicine, Kyoto, Japan, 2Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan, 3Institute for Advancement of Clinical and Translational Science (iACT), Kyoto University Hospital, Kyoto, Japan, 4Diagnostic Radiology, Kansai Electric Power Hospital, Osaka, Japan, 5Siemens Healthcare K.K., Tokyo, Japan, 6Chemical and Biological Physics, Weizmann Institute of Science, Rehovot, Israel, 7Radiology, Sheba-Medical-Center, Ramat-Gan, Israel, 8Tenri Hospital, Nara, Japan, 9Breast Surgery, Kyoto University Hospital, Kyoto, Japan

Synopsis

Keywords: Breast, BreastThis study investigated the breast lesion conspicuity and ADC reliability for 3 different DWI protocols; SPEN, SS-EPI, and RESOLVE. The in-plane resolution for SPEN and RESOLVE was 1x1mm2, and SS-EPI was 2x2mm2. SPEN showed a higher score for lesion conspicuity than SS-EPI, and a lower score than RESOLVE. ADC values in breast lesions were significantly lower in SPEN than others, presumably due to the choice of different b values, the sequences having different T1/T2 weightings, different robustness vs motions, the presence of unsuppressed fat, or different viewer systems used to analyze the data, which will need further investigation.

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Keywords