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Abstract #0200

Multidimensional RF pulse design in spin-domain using auto-differentiation for 3D refocusing pulse

Jiayao Yang1, Jon-Fredrik Nielsen2, and Yun Jiang2,3
1Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI, United States, 2Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States, 3Department of Radiology, University of Michigan, Ann Arbor, MI, United States

Synopsis

Keywords: RF Pulse Design & Fields, RF Pulse Design & FieldsThis study proposed a novel algorithm for designing multidimensional RF in spin-domain using auto-differentiation in PyTorch. Our algorithm uses spin-domain description of rotations to formulate the RF pulse design into optimization problems. We designed 3D refocusing pulses and verified the performance using spin-echo based sequences in phantom at 1.5T and in vivo in the brain at 3T.

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