Meeting Banner
Abstract #0204

Hybrid-PUSH pulses for controlled MT bias in T1 mapping at 7T

David Leitão1, Raphael Tomi-Tricot2,3, Pip Bridgen1, Patrick Liebig4, Rene Gumbrecht4, Dieter Ritter4, Jo Hajnal1,3, and Shaihan Malik1,3
1Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom, 2MR Research Collaborations, Siemens Healthcare, Frimley, United Kingdom, 3Centre for the Developing Brain, King's College London, London, United Kingdom, 4Siemens Healthcare GmbH, Erlangen, Germany

Synopsis

Keywords: RF Pulse Design & Fields, Magnetization transferWhile standard pulse design methods control the rotation of magnetization (i.e. flip angle), the recently proposed PUSH method aims to control the root-mean-squared B1, to control magnetization transfer (MT) effects. General RF pulses create both effects simultaneously: this is important in T1 mapping, where incidental MT effects introduce bias. We show that using standard pulse design methods to improve flip angle uniformity can actually worsen the bias in T1 measurement by producing uncontrolled spatially variable MT effects. We propose a ‘hybrid-PUSH’ method optimizing both flip angle and B1rms, and demonstrate this improves quality of T1 estimation in-vivo at 7T.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords