Abstract #0240

Prediction of immune status and overall survival of glioblastoma based on immune-related lncRNA signature and radiomics signature

Jixin Luan¹, Chuanchen Zhang², Di Zhang², and Guolin Ma¹

¹China-Japan Friendship Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, ²Department of Radiology, Liaocheng People's Hospital, Shandong First Medical University & Shandong Academy of Medical Sciences, Liaocheng, China

Synopsis

Keywords: Radiomics, Brain, GBMIn this study, we aimed to investigate the correlation between immune-related lncRNA signature and radiomics signature and immune cell infiltration and immune checkpoint blockade in glioblastoma multiform (GBM), and to develop a prognostic model to predict the overall survival of patients. We found that immune-related lncRNA signature and radiomics signature can better predict the immune status and overall survival of GBM patients, which can help clinical prognosis determination and immunotherapy selection.

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