Abstract #0243

Impact of Radiomic Features Stability of Myocardial Motion on Classification of Repaired Tetralogy of Fallot Patients

Pao-Han Chiu¹, Ming-Ting Wu², Ken-Pen Weng^3,4, Nai-Yu Pan⁵, Teng-Yi Huang⁵, and Hsu-Hsia Peng¹

¹Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan, ²Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ³Department of Pediatrics, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ⁴Department of Pediatrics, National Yang Ming Chiao Tung University, Taipei, Taiwan, ⁵Department of Electrical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan

Synopsis

Keywords: Radiomics, RadiomicsMyocardial motion influences the stability of radiomic features of cardiac magnetic resonance (CMR) cine images. We aimed to evaluate the impact of the stability of myocardial radiomic features on the classification performance of differentiation of repaired tetralogy of Fallot (rTOF) patients from normal volunteers. The stability of each radiomic feature during cardiac cycle was assessed by coefficient of variation (CV) of the feature value. 50 of 107 radiomic features (46.7%) in normal volunteers were stable features. The classification model established only with stable features presented the best classification performance (AUC=0.94) which was able to be improved by chi-square feature selection.

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