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Abstract #0248

Associations of Brain Iron with Cognitive and Social Emotional Performance in Children using Quantitative Susceptibility Mapping

Gaiying Li1, Qifan Pang1, Mengying Chen1, Yang Song2, Qing Cai3, Kai Zhang3, Longnian Lin3, Yi Wang4, and Jianqi Li1,3
1School of Physics and Electronic Science, East China Normal University, Shanghai, China, 2MR Scientific Marketing, Siemens, Siemens Healthineers, Shanghai, China, 3Institute of Brain and Education Innovation, East China Normal University, Shanghai, China, 4Department of Radiology, Weill Medical College of Cornell University, New York, NY, United States

Synopsis

Keywords: Data Analysis, Quantitative Susceptibility mappingTissue iron play a critical role in cognitive functions. However, associations of basal ganglia iron concentration with cognition and emotion in children are less well understood. This study examined the correlation of susceptibility values in the bilateral basal ganglia nuclei with cognitive functions and social emotional capacity in children around the age of seven. The results highlighted that the inhibitory control, collaboration, open-mindedness showed significant association with susceptibility values in the basal ganglia. In conclusion, this QSM study indicated the potential for using brain iron content in the basal ganglia to assess cognitive and emotional performance during the children development.

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