Abstract #0267

Identification of IDH and tumor subtype of adult-type diffuse gliomas based on WHO CNS5 using standard, high and ultra-high b value DWI

Xueqin Wang¹, Xinru Shu², Pingping He³, Yang Song⁴, and Rifeng Jiang⁵

¹School of Medical Imaging, Fujian Medical University, Fujian, China, ²School of Basic Medical Sciences, Fujian Medical University, Fuzhou, Fujian, China, ³School of Medical Imaging, Fujian Medical University, Fuzhou, Fujian, China, ⁴SIEMENS Healthcare, Diagnostic Imaging, Shanghai, China, ⁵Radiology, Fujian Medical University Union Hospital, Fuzhou, Fujian, China

Synopsis

Keywords: Tumors, Nervous system

To date, few studies have investigated the association between ADC values and tumor subtypes of adult-type diffuse gliomas based on WHO CNS5. By comparing standard, high and ultra-high b value DWI, our research found that all ADC values can differentiate IDH genotypes with ADC_8,000 having the highest AUC of 0.827, and mostly ADC values can differentiate the tumor subtypes of gliomas, with ADC_8,000 and ADC_4,000 having the highest AUC of 0.780 and 0.902, respectively. High and ultra-high b value DWI, is a potent approach in identifying IDH genotype and tumor subtype of adult-type diffuse gliomas based on WHO CNS5.

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