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Abstract #0280

Quantitative Comparison of Bone-Selective MRI Techniques for Craniofacial Imaging

Nada Kamona1,2, Brandon C. Jones1,2, Hyunyeol Lee1,3, Connor S. Wagner4, Makayla Clark1, Advait Thaploo1, Sandhya Konar1, Carlos Mendez Cruz1, Kevin Li1, Bartlett P. Bartlett4, Chamith S. Rajapakse1,5, Hee Kwon Song1, and Felix W. Wehrli1
1Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States, 2Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, United States, 3School of Electronics Engineering, Kyungpook National University, Daegu, Korea, Republic of, 4Division of Plastic, Reconstructive, and Oral Surgery, Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, PA, United States, 5Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, United States

Synopsis

Keywords: Quantitative Imaging, Bone, Skull imagingRisk of ionizing radiation from CT remains a concern for pediatric patients, such as craniosynostosis patients who may require multiple scans at a young age. We quantitatively compared three MRI methods for imaging the skull by scanning healthy adults using our solid-state bone-selective ultrashort echo subtraction sequence, along with zero echo time and gradient-echo sequences. We demonstrate the similarities among the 3D rendered bone segmentations in terms of Dice similarity coefficient and craniometric measurements across all imaging methods. Our UTE echo subtraction technique shows clear visualization of craniofacial structures near the bone-air boundaries and superior signal suppression of soft-tissues.

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