Abstract #0309

MUSE reconstruction of multishot DW-EPI is not limited by SNR at 0.5T

Ally Klassen¹, James Rioux^2,3, Chris Bowen³, Curtis Wiens⁴, Sharon Clarke^5,6, and Steven Beyea^3,7

¹Biomedical Engineering, Dalhousie University, Halifax, NS, Canada, ²BIOTIC / Biomedical Translational Imaging Centre, Nova Scotia Health, Halifax, NS, Canada, ³Physics and Atmospheric Science, Dalhousie University, Halifax, NS, Canada, ⁴Synaptive Medical, Toronto, ON, Canada, ⁵Diagnostic Radiology, Dalhousie University, Halifax, NS, Canada, ⁶Diagnostic Radiology, Nova Scotia Health, Halifax, NS, Canada, ⁷BIOTIC / Biomedical Translational Imaging Centre, IWK Health, Halifax, NS, Canada

Synopsis

Keywords: Low-Field MRI, Susceptibility, Susceptibility distortionMulti-shot echo planar imaging (EPI) can be used to reduce spatial distortion and improve spatial resolution in diffusion-weighted imaging; however, patient motion between shots can result in large intra-shot phase differences and increased artifact. It is unknown whether multiplexed sensitivity encoding (MUSE) can be applied to reduce these phase differences in DW-EPI images acquired at low field due to the inherently lower SNR. In this work we evaluate the performance of MUSE in DW-EPI data acquired at 0.5T, in terms of SNR and ghost-to-noise ratio (GNR) as a function of signal averaging, and demonstrate that multi-shot DW-EPI is feasible.

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