Abstract #0316

THE ADDED VALUE OF HYBRID MULTIDIMENSIONAL MRI TO MULTIPARAMETRIC MRI IN DIAGNOSING CLINICALLY SIGNIFICANT PROSTATE CANCERS

Grace Lee¹, Aritrick Chatterjee¹, Ibrahim Karademir¹, Roger Engelmann¹, Ambereen Yousuf¹, Mihai Giurcanu², Carla Harmath¹, Gregory Karczmar¹, and Aytekin Oto¹

¹RADIOLOGY, University of Chicago, Chicago, IL, United States, ²BIOSTATISTICS, University of Chicago, Chicago, IL, United States

Synopsis

Keywords: Prostate, Quantitative Imaging, Multiparametric MRI

1. In a retrospective review of 61 men by four readers, two inexperienced-readers had higher accuracy using multiparametric MRI+Hybrid-Multidimensional MRI (mpMRI+HM-MRI)=82%,81% versus Multiparametric MRI=77%, 71% (p=.006,<.001) and higher specificity=89%,88% versus 84%,75% (p=.009, p<.001) on a per-sextant analysis.

2. Multiparametric MRI+Hybrid-Multidimensional MRI increased trainee specificity=46% versus Multiparametric MRI=7% (p<.001) on a per-patient analysis.

3. Multiparametric MRI+Hybrid-Multidimensional MRI increased interreader Kappa agreement=0.36 versus Multiparametric MRI (mpMRI) Kappa=0.17 (p=0.009) in diagnosing clinically significant prostate cancer (CS PCa).

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