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Abstract #0325

18F-PSMA-1007 PET/MR compared to PET/CT in prostate cancer recurrence: impact on clinical management

Bendik Skarre Abrahamsen1, Trond Velde Bogsrud2,3, Eivor Hernes4, Torgrim Tandstad5,6, Sverre Langørgen7, Miguel Castillejo2, Kirsten Margrete Selnæs7, Ingerid Skjei Knudtsen1, Thomas Morten Ingmar Keil7, Håkon Johansen7, Tone Frost Bathen1,7, and Mattijs Elschot1,7
1Derpartment of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway, 2PET Imaging Centre, University Hospital of North Norway, Tromsø, Norway, 3PET-Centre, Aarhus University Hospital, Aarhus, Denmark, 4Department of nuclear medicine, Oslo University Hospital, Oslo, Norway, 5The Cancer Clinic, St. Olavs Hospital, Trondheim, Norway, 6Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway, 7Department of Radiology and Nuclear Medicine, St. Olavs Hospital, Trondheim, Norway

Synopsis

Keywords: Prostate, PET/MR

For patients with suspected prostate cancer recurrence, we examined the added value of 18F-PSMA-1007 PET to MR and CT imaging, and whether choice of PET modality, i.e. PET/MR or PET/CT, had an impact on clinical management. An intention-to-treat analysis was performed using findings from MR and CT alone, MR and CT with PET from PET/CT, and MR and CT with PET from PET/MR. Addition of 18F-PSMA PET changed clinical management in over 40% of patients. Differences in clinical management between PET/CT and PET/MR were smaller than adding any PET modality to MR and CT.

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Abstract Presentation Video

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