Abstract #0330

Efficient fat suppression in free-running whole-heart CMR using OptiPulse

Xavier Sieber¹, Ludovica Romanin^1,2, Chris W. Roy¹, Jessica AM Bastiaansen^3,4, Jérôme Yerly¹, Jonas Richiardi¹, Matthias Stuber^1,5, and Ruud B. van Heeswijk¹

¹Department of Diagnostic and Interventional Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, ²Advanced Clinical Imaging Technology, Siemens Healthineers International AG, Lausanne, Switzerland, ³Department of Diagnostic, Interventional and Pediatric Radiology (DIPR), Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland, ⁴Translation Imaging Center (TIC), Swiss Institute for Translational and Entrepreneurial Medicine, Bern, Switzerland, ⁵Division of Cardiology, CIBM Center for Biomedical Imaging, Lausanne, Switzerland

Synopsis

Keywords: Vessels, RF Pulse Design & FieldsThe incomplete or time-inefficient suppression of fat signals is an unsolved issue in 3D cardiovascular MR imaging (CMR). We present a flexible framework named OptiPulse to design spectrally-selective radiofrequency (RF) pulses using numerical optimization of Bloch equation simulations. The RF pulse performance was assessed using a composite loss function for both fat suppression and power requirement. OptiPulse was used to design a B-splines-interpolated pulse for use in a free-running 3D whole-heart pulse sequence. Its fat suppression performance was ascertained both in vitro and in vivo, where it resulted in more homogeneous fat suppression when compared to other WE pulses (P<0.01).

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