Abstract #0334

Cardiac structure discontinuities revealed by ex-vivo microstructural characterization on the Basal Inferoseptal Left Ventricle region.

Pierre CABANIS^1,2, Julie MAGAT^1,2, Jairo RODRIGUEZ-PADILLA³, Girish RAMLUGUN², Maxime YON², Yann BIHANPOUDEC⁴, Nestor PALLARES-LUPON², Fanny VAILLANT², Philippe PASDOIS², Pierre JAIS^2,5, Pierre DOS-SANTOS^2,5, Marion CONSTANTIN², David BENOIST², Line POURTAU², Virginie DUBES², Julien ROGIER^2,5, Louis LABROUSSE^2,5, Michel HAISSAGUERRE^2,5, Olivier BERNUS², Bruno QUESSON^1,2, Richard WALTON², Josselin DUCHATEAU^2,5, Edward VIGMOND², and Valéry OZENNE^1,2

¹Univ. Bordeaux, CNRS, CRMSB, UMR 5536, Bordeaux, France, ²Liryc, Electrophysiology and Heart Modeling Institute, Fondation Bordeaux Université, Pessac-Bordeaux, France, ³Inria Epione Team, Université Côte d'Azur, Biot, France, ⁴Centre de Neuroscience Cognitive, CNRS, Université Claude Bernard Lyon I, Villeurbanne, France, ⁵Cardiology Departement, Bordeaux University Hospital (CHU), Pessac, France

Synopsis

Keywords: Myocardium, Microstructure, FiberThe knowledge of the cardiac microstructure and the 3D myofiber architecture grow years after years with the multiplication and the upgrade of imaging technologies. However, the course of events of pathophysiological processes like cardiac remodeling, and the link with clinical phenotypes are not yet clearly understood. Some concerns have been raised regarding the interpretation of the late gadolinium enhancement (LGE) at the right ventricle attachment or insertion point (RVIP) however 3D microstructure organization of the RVIP has not been extensively described in the literature.

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