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Abstract #0340

Joint cardiac $$$T_1$$$ mapping and cardiac cine using a deep manifold framework

Qing Zou1, Sarv Priya2, Prashant Nagpal3, and Mathews Jacob2
1University of Texas Southwestern Medical Center, Dallas, TX, United States, 2University of Iowa, Iowa City, IA, United States, 3University of Wisconsin–Madison, Madison, WI, United States

Synopsis

Keywords: Heart, Machine Learning/Artificial Intelligence, ReconstructionThe main focus of this work is to introduce a deep generative model for simultaneous free-breathing cardiac $$$T_1$$$ mapping and CINE MRI. The data is acquired by a gradient echo inversion recovery sequence with intermittent delays for magnetization recovery. The joint reconstruction of the image time-series is performed using a patient-specific deep manifold reconstruction algorithm which learns a CNN generative model and its latent vectors from the measured k-t space data in an unsupervised fashion. Following learning, the model can be used to generate synthetic images at specific motion and contrast states.

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Keywords