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Abstract #0345

Simplified Protocol with mSAVA for 3D Imaging of T1, T2, Extracellular Volume, Bright-Blood and Dark-Blood Late Gadolinium Enhancement

Dongyue Si1, Lan Cheng2,3, Xiangchuang Kong2,3, Rui Guo4, Daniel A. Herzka5, and Haiyan Ding1
1Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University, Beijing, China, 2Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China, 3Hubei Province Key Laboratory of Molecular Imaging, Wuhan, China, 4School of Medical Technology, Beijing Institute of Technology, Beijing, China, 5Department of Radiology, Case Western Reserve University, Cleveland, OH, United States

Synopsis

Keywords: Cardiomyopathy, Tissue Characterization

Multi-parametric SAturation recovery and Variable flip Angle (mSAVA) acquires four 3D volumes with different T1 and T2 weightings during free-breathing to simultaneously generate whole heart T1 and T2 parametric maps. We proposed a fast and simple CMR protocol using pre- and post-contrast mSAVA acquisitions to additionally generate ECV maps, and bright-blood and dark-blood LGE images. mSAVA could comprehensively assess the myocardium over the whole heart within ~6+6 min in a cohort of twenty patients.

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