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Abstract #0363

A 3D Fast Multiphase DENSE MRE Sequence with Stack-of-Star Radial Sampling, Interleaved Multi-Slab Acquisition and Hadamard Encoding

Yu Chen1, Runke Wang1, Ruokun Li2, Fuhua Yan2, and Yuan Feng1,2,3
1Shanghai JiaoTong University, School of Biomedical Engineering, Shanghai, China, 2Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China, 3Institute of Medical Robotics, Shanghai Jiao Tong University, Shanghai, China

Synopsis

Keywords: Elastography, BrainConventional gradient echo (GRE) based Magnetic Resonance Elastography (MRE) suffers from long TE and scan time at low mechanical excitation (<25Hz). Displacement Encoding with a Stimulated Echo (DENSE) can record displacement with short TR, useful for low-frequency excitation. Here, 3D excitation was used to compensate for potential signal loss. A multiphase acquisition scheme with stack-of-star radial sampling was also used along with interleaved multi-slab acquisition and Hadamard encoding for MRE acceleration. Phantom experiments were conducted for validation. 32 slices brain MRE scan at 20Hz can be achieved in 11min30s, 5 folds faster than conventional GRE-based MRE.

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Keywords