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Abstract #0423

Semi-Supervision for Clinical Contrast-Weighted Image Synthesis from Magnetic Resonance Fingerprinting

Mahmut Yurt1, Cagan Alkan1, Sophie Schauman1,2, Xiaozhi Cao1,2, Congyu Liao1,2, Siddharth Iyer1,3, Tolga Cukur4, Shreyas Vasanawala2, John Pauly1, and Kawin Setsompop1,2
1Department of Electrical Engineering, Stanford University, Stanford, CA, United States, 2Department of Radiology, Stanford University, Stanford, CA, United States, 3Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, 4Department of Electrical Engineering, Bilkent University, Ankara, Turkey

Synopsis

Keywords: MR Fingerprinting/Synthetic MR, MR FingerprintingPrevious works have introduced deep models to synthesize clinical contrast-weighted images from magnetic resonance fingerprinting (MRF). Although these models achieve high synthesis accuracy, they demand full-supervision from fully-sampled training data of clinical contrasts which might become difficult to acquire across diverse sets due to scan costs. To eliminate undesirable reliance on full-supervision, we introduce a semi-supervised model, ssMRF, that allows training using accelerated references. ssMRF introduces a semi-supervised loss function based only on collected k-space samples of clinical contrasts, and further leverages complementary Poisson disc masks, via a multi-task learning protocol to synergistically synthesize multiple contrasts.

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Keywords