Abstract #0426

Simultaneous Quantification of Relaxation and Diffusion using MR Fingerprinting with Self-Calibrated Subspace Reconstruction

Zhilang Qiu¹, Siyuan Hu¹, Walter Zhao¹, Ken Sakaie², Mark A. Griswold³, Derek K. Jones⁴, and Dan Ma¹

¹Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, ²Imaging Institute, Cleveland Clinic, Cleveland, OH, United States, ³Radiology, Case Western Reserve University, Cleveland, OH, United States, ⁴Cardiff University Brain Research Imaging Centre (CUBRIC), School of Psychology, Cardiff University, Cardiff, United Kingdom

Synopsis

Keywords: MR Fingerprinting/Synthetic MR, Diffusion/other diffusion imaging techniquesWe propose a self-calibrated subspace reconstruction method for multidimensional MR Fingerprinting (mdMRF) scan for simultaneous relaxation and diffusion mapping without pulsation gating. It is distortion-free, unlike EPI-based diffusion MRI. MRF images corrupted by phase errors due to bulk and physiological motions are automatically detected using an outlier detection algorithm and corrected, in order to generate artifact-free relaxation and diffusion maps.

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