Keywords: MR Fingerprinting/Synthetic MR, Tissue Characterization, degenerative
The study investigated age and gender differences in intervertebral disc (IVD) of the lumbar spine using a multiparameter MR fingerprinting (MRF) technique that simultaneously quantify T1, T2 and T1ρ. Seventeen healthy subjects were evaluated. There was a significant positive association between age and T1ρ of the IVD and between age and various gray level co-occurrence matrix features of T1 maps on texture analysis. There were no significant differences between males and females in T1, T2 and T1ρ of the IVD. The results demonstrate that multi-parameter MRF can effectively characterize early age-related IVD degeneration.
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