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Abstract #0439

Radiomics of Multiparametric MRI in Tumor Grading of Endometrial Cancer

Yiang Wang1, Mengge He1, Peng Cao1, Chien-Yuan Lin2, Weiyin Liu2, Chia-Wei Lee2, and Elaine Y.P. Lee1
1Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong, Hong Kong, 2GE Healthcare, Taipei, Taiwan

Synopsis

Keywords: Uterus, Cancer, Endometrial Cancer; Tumor Grade

Random forest models were constructed to predict tumor grade (grade 1-2 vs. grade 3) of endometrial cancer based on radiomics features extracted from quantitative T1, T2, proton density maps generated by synthetic MRI and apparent diffusion coefficient maps generated by diffusion-weighted imaging. The classification model based on features extracted from all the quantitative maps achieved the highest area under the curve of 0.804 compared to models constructed based on single quantitative map.

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Keywords