Abstract #0446

Assessing within-subject rates of change of placental magnetic resonance imaging diffusion metrics

Daniel Cromb^1,2, Paddy J Slator³, Anthony Price^1,2, Miguel De La Fuente¹, Alexia Egloff-Collado¹, Mary Rutherford^1,4, Serena J Counsell^1,2, and Jana J Hutter^1,2

¹Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, ²Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, ³Centre for Medical Image Computing, Department of Computer Science, University College London, London, United Kingdom, ⁴MRC Centre for Neurodevelopmental Disorders, King's College London, London, United Kingdom

Synopsis

Keywords: Placenta, PlacentaThis study provides unique data on the evolution of quantitative multi-modal placenta MRl measures over gestation, including, crucially, within-subject results. A multi-compartmental T2*-IVIM model was employed, suited to the complex physiology of the human placenta, and matched to the deployed multi-parametric acquisition technique.

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