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Abstract #0447

The effects of maternal flow on placental DWI data

George Hutchinson1, Adam Blakey2, Neele Dellschaft1, Nia Jones3, Reuben O'Dea2, Lopa Leach4, Matthew Hubbard2, Paul Houston2, and Penny Gowland1
1The Sir Peter Mansfield Imaging Centre, The University of Nottingham, Nottingham, United Kingdom, 2Mathematical Sciences, The University of Nottingham, Nottingham, United Kingdom, 3Medicine, The University of Nottingham, Nottingham, United Kingdom, 4Life Sciences, The University of Nottingham, Nottingham, United Kingdom

Synopsis

Keywords: Placenta, Diffusion/other diffusion imaging techniquesPlacental diffusion imaging data is assumed to be driven by a combination of slow diffusive processes, as well as faster incoherent terms. How these faster incoherent terms combine within a voxel is not obvious, and here we investigate this further by comparing a mathematical simulation of maternal flow through a single placentone to data collected in utero. We observe maternal flows can cause IVIM like effects, with slow exponential decays, but also regions of fast IVIM similar to those observed in the placenta, as well as 'rebounding' of signal.

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