Keywords: Multiple Sclerosis, Contrast AgentMultiple sclerotic (MS) patients undergo routine MRI examination in order to monitor disease state and progression. The gold standard way to assess disease activity is by identifying the amount of active lesions using contrast enhanced imaging. The use of gadolinium-based contrast agents constitute a major radiologic concern as these are known to accumulate in the body for years without an effective clearance mechanism. In this study we investigated the utility of Radiomic profiling of lesions as an alternative for contrast injection. We show that the quantitative MRI (qMRI) markers have the potential to classify lesions to active/inactive.
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