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Abstract #0458

MRI Detection of Glymphatic Function in athletes after Sports-related Concussion

Laiyang Ma1, Wanjun Hu1, Jing Zhang1, Wenjing Huang1, and Yuhui Xiong2
1Department of Magnetic Resonance, Lanzhou University Second Hospital, Lanzhou, China, 2MR Research, GE Healthcare MR Research, Beijing, China

Synopsis

Keywords: Traumatic brain injury, Diffusion/other diffusion imaging techniquesDiffusion tensor image analysis along the perivascular space (DTI-ALPS) as a non-invasive method for evaluating the activity of the glymphatic system in human brain by using diffusion images. In this study, DTI-ALPS was used to evaluate the activity of the human lymphatic system in patients with Sports-related concussion (SRC). We found SRC has a higher ALPS index compared to the healthy controls. Our findings suggested that abnormal glymphatic function in brain might be a potential biomarker for explaining the cognitive function decline of SRC.

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