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Abstract #0473

Removal of Water and Lipid Signals from J-resolved 1H-MRSI Data Using an FID Reference and Physics-Based Subspaces

Wen Jin1,2, Yibo Zhao1,2, Yudu Li1,3, Rong Guo1,4, Ruihao Liu1,5, Jie Luo5, Yao Li5, and Zhi-Pei Liang1,2
1Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 2Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 3National Center for Supercomputing Applications, University of Illinois at Urbana-Champaign, Urbana, IL, United States, 4Siemens Medical Solutions USA, Inc., Urbana, IL, United States, 5School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China

Synopsis

Keywords: Data Processing, SpectroscopyJ-resolved 1H-MRSI provides a unique capability to quantify both brain neurotransmitters and metabolites. This paper presents a novel method to effectively remove water and lipid signals from J-resolved 1H-MRSI data with limited spatial encodings and without lipid suppression. The proposed method has been validated using data from a healthy subject and a brain tumor patient, producing impressive results.

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