Abstract #0486

Detecting the role of hippocampal subfields in pattern separation and completion task using 7T object memory task fMRI

Zhengshi Yang¹, Xiaowei Zhuang², Mark Lowe³, and Cordes Dietmar¹

¹Lou Ruvo Center for Brain Health, Cleveland Clinic, Las Vegas, NV, United States, ²Cleveland Clinic, Las Vegas, NV, United States, ³Cleveland Clinic, Cleveland, OH, United States

Synopsis

Keywords: Data Analysis, fMRI, Task fMRI; reigstrationIn this study, we have established a reliable hippocampal subfield segmentation and activation analysis pipeline to probe the role of hippocampal subfields in pattern separation task by using 7T fMRI data, which could be able to identify the role of subfield dysfunction in cognitive impairment in prodromal AD.

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