Meeting Banner
Abstract #0513

Comparison of 31P MRS in human pancreas and liver at 7 Tesla

Leonard W.F. Seelen1,2, Lieke van den Wildenberg1, Ayhan Gursan1, W.J. Mark Gosselink1, Wybe J.M. van der Kemp1, Firdaus A.A. Mohamed Hoesein3, Nadia Haj Mohammad4, I. Quintus Molenaar2, Hjalmar C. van Santvoort2, Dennis W.J. Klomp1, and Jeanine J. Prompers1
1Center for Image Sciences, University Medical Center Utrecht, Utrecht, Netherlands, 2Dept. of Surgery, UMC Utrecht Cancer Center and St Antonius Hospital Nieuwegein: Regional Academic Cancer Center Utrecht, Utrecht University, Utrecht, Netherlands, 3Dept. of Radiology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands, 4Dept. of Medical Oncology, UMC Utrecht Cancer Center, Regional Academic Cancer Center Utrecht, Utrecht University, Utrecht, Netherlands

Synopsis

Keywords: Pancreas, Non-Proton

31P MRS could be valuable for the assessment of treatment response in pancreatic cancer. Using a 31P whole-body transmit coil in combination with a 16-channel receive array at 7T, we could obtain 31P MRSI data covering both the whole liver and the deeply lying pancreas. The aim of this study was to compare 31P metabolite levels in the pancreas and liver in healthy volunteers. The PME/PDE ratio, which has been used as a tumor marker, was 2.1-fold higher in the pancreas compared to the liver. This will be important to take into account when applying 31P MRS in pancreatic tumors.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Abstract Presentation Video

Keywords