Abstract #0518

Correlations between adipose tissue volume changes and its baseline MR-characteristics in people with obesity undergoing a caloric restriction

Daniela Junker¹, Mingming Wu¹, Selina Rupp¹, Jessie Han¹, Stella Näbauer¹, Anna Reik², Meike Wiechert², Arun Somasundaram¹, Marcus R. Makowski¹, Hans Hauner², Christina Holzapfel², and Dimitrios C. Karampinos¹

¹Department of Diagnostic and Interventional Radiology, School of Medicine, Technical University of Munich, Munich, Germany, ²Institute for Nutritional Medicine, School of Medicine, Technical University of Munich, Munich, Germany

Synopsis

Keywords: Endocrine, FatResults of weight loss interventions differ individually. MRI-based quantification and characterization of adipose tissue (AT) offers methods to identify possible AT-phenotypes that facilitate AT loss. The purpose of this analysis was to evaluate how, in people with obesity undergoing an 8-week formula-based weight loss intervention, the relative AT and lipid volume loss of the subcutaneous and visceral AT depot correlate to the proton density fat fraction (PDFF) and the total volume of AT as well as the volume of lipids in each depot at the beginning of the diet.

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