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Abstract #0521

A Pretrained CNN Model Using Multiparametric MRI to Identify WHO Tumor Grade of Meningiomas

Sena Azamat1,2, Buse Buz-Yaluğ1, Alpay Ozcan3, Ayça Ersen Danyeli4,5,6, Necmettin Pamir5,7, Alp Dinçer4,8, Koray Ozduman4,7, and Esin Ozturk-Isik1,4
1Institute of Biomedical Engineering, Bogazici University, Istanbul, Turkey, 2Department of Radiology, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey, 3Electric and Electronic Engineering Department, Bogazici University, Istanbul, Turkey, 4Brain Tumor Research Group, Acibadem University, Istanbul, Turkey, 5Center for Neuroradiological Applications and Reseach, Acibadem University, Istanbul, Turkey, 6Department of Medical Pathology, Acibadem University, Istanbul, Turkey, 7Department of Neurosurgery, Acibadem University, Istanbul, Turkey, 8Department of Radiology, Acibadem University, Istanbul, Turkey

Synopsis

Keywords: Tumors, Machine Learning/Artificial IntelligenceMeningiomas are the most common primary extra-axial intracranial tumors in adults. Grade of meningioma helps to predict the patient prognosis. Sixty-two patients with preoperative MRI were included in this IRB approved study. The whole tumor volumes were segmented from FLAIR, followed by co-registration onto SWI. A pretrained convolutional neural network (CNN) was employed to classify meningiomas into high and low-grades based on SWI, CE-T1W and FLAIR MRI. The pretrained CNN with data augmentation resulted in an accuracy of 80.2% (sensitivity=82.6% and specificity=78.1%) for identifying grades in meningiomas.

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