Abstract #0548

Fetal cardiac 3D cine MRI at low field - whole heart slice-to-volume reconstruction from real-time spiral SSFP at 0.55T

Joshua F P van Amerom¹, Ye Tian², Datta S Goolaub¹, John Wood^3,4, Jon Detterich⁴, Krishna S Nayak², and Christopher K Macgowan^1,5

¹Translational Medicine, Hospital for Sick Children, Toronto, ON, Canada, ²University of Southern California, Los Angeles, CA, United States, ³Department of Biomedical Engineering, University of Southern California, Los Angeles, CA, United States, ⁴Division of Cardiology, Children's Hospital Los Angeles, Los Angeles, CA, United States, ⁵Department ofMedical Biophysics, University of Toronto, Toronto, ON, Canada

Synopsis

Keywords: Heart, Fetus, Cine, 4D, Whole Heart, MorphologySpiral SSFP of the fetal heart at low-field has the advantage of low artifact and high sampling efficiency, compared to conventional systems. This work demonstrates the feasibility of spiral SSFP on a high-performance 0.55 T scanner to produce high spatiotemporal resolution real-time 2D and motion-corrected slice-to-volume super-resolution reconstructed 3D cine images of the heart and great vessels of the human fetus in utero. Patient comfort is improved with the use of a low-field scanner, while motion-robust slice-to-volume reconstruction allows for free-breathing acquisitions that do not require precise scan plane prescriptions during acquisition.

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