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Abstract #0550

Highly Accelerated Cartesian Real-Time Cine CMR Using Subject-Specific Zero-Shot Deep Learning Reconstruction

Omer Burak Demirel1,2, Chi Zhang1,2, Burhaneddin Yaman1,2, Merve Gulle1,2, Tim Leiner3, Peter Kellman4, and Mehmet Akçakaya1,2
1Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, United States, 2Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, 3Department of Radiology, Mayo Clinical, Rochester, MN, United States, 4National Heart-Lung and Blood Institute, Bethesda, MD, United States

Synopsis

Keywords: Heart, HeartReal-time cine CMR is an ECG-free free-breathing alternative for functionally assessing the heart. To achieve sufficient spatio-temporal resolutions, these require rapid imaging, e.g. compressed sensing (CS) with radial trajectories. However, at high accelerations, CS may suffer from residual aliasing and temporal blurring. Recently, deep learning (DL) reconstruction has gained immense interest for fast MRI. Yet, for free-breathing real-time cine, where subjects have different breathing and cardiac motion patterns, database learning of spatiotemporal correlations has been difficult. Here, we propose a physics-guided DL reconstruction trained in a subject-specific manner. Proposed method improves image quality compared to database-trained DL and conventional methods.

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Keywords