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Abstract #0555

Intra-bin correction and inter-bin compensation of respiratory motion in free-running 5D whole-heart MRI

Christopher W. Roy1,2, Bastien Milani1,2, Jérôme Yerly1,2,3, Salim Si-Mohamed1,4,5, Estelle Tenisch1,2, Tobias Rutz2,6, Milan Prsa2,7, Ludovica Romanin1,2,8, Aurélien Bustin9,10, Davide Piccini1,8, and Matthias Stuber1,2,3
1Diagnostic and Interventional Radiology, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland, 2University of Lausanne, Lausanne, Switzerland, 3Center for Biomedical Imaging (CIBM), Lausanne, Switzerland, 4University Lyon, Lyon, France, 5Radiology, Louis Pradel Hospital, Lyon, France, 6Service of Cardiology, Heart and Vessel Department, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland, 7Division of Pediatric Cardiology, Woman-Mother-Child Department, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland, 8Advanced Clinical Imaging Technology, Siemens Healthcare International AG, Lausanne, Switzerland, 9IHU LIRYC, Electrophysiology and Heart Modeling Institute, Université de Bordeaux, Bordeaux, France, 10Department of Cardiovascular Imaging, Hôpital Cardiologique du Haut-Lévêque, Bordeaux, France

Synopsis

Keywords: Heart, Motion CorrectionIn this work, we develop, validate, and apply a novel reconstruction framework for intra-bin correction and inter-bin compensation of respiratory motion in cardiac and respiratory motion-resolved free-running whole heart 5D MRI. We demonstrate respiratory resolved images with reduced artifact and without compressing the underlying physiological motion providing a means to increase the acquired resolution, accelerate the acquisition, or investigate respiratory driven changes in cardiac output and blood flow, potentially leading to new MRI driven biomarkers for cardiovascular disease

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