Abstract #0597

Ultra-low-field Magnetization Transfer Imaging with Low SAR

Shi Su^1,2, Yujiao Zhao^1,2, Vick Lau^1,2, Linfang Xiao^1,2, Ye Ding^1,2, Jiahao Hu^1,2, Junhao Zhang^1,2, Christopher Man^1,2, Alex T. L. Leong^1,2, and Ed X. Wu^1,2

¹Laboratory of Biomedical Imaging and Signal Processing, the University of Hong Kong, Hong Kong, China, ²Department of Electrical and Electronic Engineering, the University of Hong Kong, Hong Kong, China

Synopsis

Keywords: Low-Field MRI, Contrast MechanismsAt high field, magnetization transfer (MT) imaging suffers from the high specific absorption ratio (SAR) issue due to the usage of high power off-resonance MT RF pulses, and on-resonance saturation caused by B0 field inhomogeneity. At ultra-low-field (ULF), the low SAR and low absolute B0 inhomogeneity (in Hz) greatly facilitates the application of strong and versatile MT pulses without the confounding on-resonance saturation in practice. We demonstrate brain MT imaging at ULF first the first time using a 0.055 Tesla MRI platform with an extremely low SAR.

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